Researchers at the University of Copenhagen have developed a groundbreaking nanofibre patch that promises a more effective and convenient treatment for psoriasis, one of the most common inflammatory skin conditions globally. Affecting 4-5% of Denmark’s population, psoriasis manifests as red, scaly rashes of varying severity and currently requires treatments such as creams, ointments, radiation, or medication.
The innovative patch, created using electrospinning technology, simplifies the treatment process by reducing the frequency of application to once a day. “We’ve developed a dry patch containing active ingredients for psoriasis treatment, making it more comfortable for plaque psoriasis patients,” explained Andrea Heinz, associate professor at the university’s Department of Pharmacy.
The patch is designed to deliver two active ingredients in a controlled manner:
- Salicylic acid, released immediately, removes accumulated dead skin cells.
- Hydrocortisone, released gradually, reduces inflammation over time.
This dual-action delivery system not only matches the efficacy of conventional creams and ointments but also offers the potential for better user compliance due to its simplicity. “We tested the prototype on pig skin and human skin cells and found it just as effective as standard treatments,” said PhD student Anna-Lena Gürtler.
While the prototype has shown promising results, further research, development, and clinical trials are required before the patch becomes commercially available. Beyond psoriasis, the nanofibre patch could revolutionize treatment for other inflammatory skin conditions, such as atopic eczema, or even aid in wound healing.
“This approach offers an alternative to traditional creams and ointments, opening up possibilities for treating a range of skin conditions with greater precision and convenience,” Heinz added.
This innovation highlights the potential of nanotechnology in advancing dermatological treatments, bringing hope to millions affected by chronic skin conditions.
For more information, visit sund.ku.dk.
